The presence of insulin resistance and elevated pro-inflammatory cytokines (e.g., tumor necrosis factor-) induce hepatic GH resistance (64), causing increases in GH and decreases in IGF-I levels ( Table 1 )
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[DOI] [PMC free article] [PubMed] 12.Ahmadian M., Roshan V.D., Aslani E., Stannard S.R
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Although the existence of mtNOS has been described in mitochondrial fractions from different organs, recent evidence in rat liver mitochondria has questioned the existence of mtNOS, minimizing the contribution of in situ NO generation within mitochondrial to the formation of peroxynitrite (Venkatakrishnan et al., 2009)
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