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G.van GeldermalsenM.et al (2014)

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Never use frozen or previously frozen GLP-1 injections, and always carry medication in hand luggage to avoid cargo hold temperature extremes

The peptide is constructed on a GIP receptor backbone with non-coded amino acid residues (Aib2, Aib20, aMeL13) and a C20 fatty diacid moiety that enables albumin binding, extending pharmacokinetic half-life for once-weekly administration in research settings

Patients can expect to start seeing some benefits within four weeks from starting semaglutide therapy