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Nolan et al., 2019), while human THP-1 monocytic cells have substantially higher levels of D4, particularly relative to D1-like receptor expression (Basova et al., 2018)

Other studies suggest that D3 activity may be anti-inflammatory in mast cells, as there is a negative correlation between the numbers of D3-expressing mast cells in synovial fluid and disease severity in RA (Xue, Li et al., 2018)

Promotes healthy gastrointestinal system function

[DOI] [PubMed] [Google Scholar] Posner J, Polanczyk GV, Sonuga-Barke E (2020) Attention-deficit hyperactivity disorder

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This makes it particularly valuable for patients whose skin sensitivity limits their use of more aggressive actives like retinoids