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483 Moreover, MT suppresses Ang II-induced NOX-dependent nitrosative damage and cell death in both nondiabetic and diabetic hearts early in the injury process, effectively preventing the later development of Ang II-induced cardiomyopathy

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The enzyme-catalyzed reverse reaction between GSSG or GSSR and reduced roGFP2 releases roGFP2(SSG) which can instantaneously react via a nonenzymatic shortcut yielding GSH and roGFP2(S 2 ) (Fig

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