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Failure of these glutamatergic strategies is consistent with the lack of efficacy of various other non-dopaminergic approaches including adjunctive pharmacotherapy with anticholinesterase inhibitors, antidepressants, anti-oxidants, mood stabilizers, anti-inflammatory agents, hormone replacements or stimulants [134]

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9Eshows the effect of different formulations of cisplatin on caspase activation.FIG