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(10 g or 10 ng/kg/day), topical (1.0 g in cream), or per-oral (0.16 g/mL in drinking water) over 90 days and described directional improvements across biomechanical, functional, macroscopic, and histological endpoints, though specific effect sizes and p-values are not reported in the abstract

10.1097/BRS.0b013e318266a80d

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In each method solvents A and B comprising of water-acetonitrile-formic acid (90:10:0.1, v/v/v) and methanol-acetonitrile-formic acid (90:10:0.1, v/v/v), respectively were used

BAC water is commonly used for reconstituting multi-dose injectable drugs such as peptides