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[7] Much research has demonstrated a direct correlation between a breakdown in the glutathione system and autoimmune disease
Melatonin is synthesized in the pineal gland through the activation of two key enzymes: AANAT (arylalkylamine N-acetyltransferase) pCREB (phosphorylated cAMP response element-binding protein) In rat pinealocytes, Epitalon was shown to upregulate both AANAT and pCREB, suggesting a direct enzymatic stimulation of melatonin biosynthesis [56]
It is advised to have it with a glass of water or mixed with a liquid
2019;44(1):e13100
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