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Begin with the retatrutide protocol alone, establish tolerability, confirm that the primary compound is producing the expected effects, and only then consider carefully selected adjuncts based on specific, measurable goals

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Policy The findings support continuing the use of GLP-1 medications in women with metabolic risk factors who are considering pregnancy, says Cara Dolin, MD, a maternal-fetal medicine specialist, and a coauthor of the research, which was presented at the Society of Maternal-Fetal Medicine pregnancy meeting in February 2026