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Several research groups are investigating strategies to induce hepcidin expression, and the emergence of CRISPR-CAS gene-editing technology has enabled proof-of-concept gene therapy for single-base pair mutations

As observed in this research, some prior results reported that DPP-4 inhibitors and Quercetin may reduce glycemic variations in the diabetes model 12,13 , however clinical trials and other research in T1DM indicate that administration of each of these agents separately is not consistent in altering glycemic parameters 8,14 , that is, results are conflicting and the final outcomes are inconclusive

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