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For many individuals, the natural signaling of GLP-1 can be less effective due to genetics, environment, or existing metabolic conditions

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Quadri P, Fragiacomo C, Pezzati R, Zanda E, Forloni G, Tettamanti M, Lucca U (2004) Homocysteine, folate, and vitamin B-12 in mild cognitive impairment, alzheimer disease, and vascular dementia

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