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A direct head-to-head trial (NCT06662383, 800 patients) is underway with results in December 2026

Most patients receive their medication within 35 business days of approval

Gastrointestinal Effects The most commonly reported adverse effects are gastrointestinal in nature, including: Nausea and vomiting (affecting 20-40% of patients initially, varying by agent and dose) [8] Diarrhoea or constipation Abdominal discomfort and bloating Reduced appetite In elderly patients, persistent nausea and vomiting can lead to dehydration and electrolyte imbalances more rapidly than in younger adults

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If it doesn't improve or gets severe, talk to your doctor don't just push through it

Physiol Behav (2008) 93(45):85161