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J Clin Invest 2024;134:e178239.ArticlePubMedPMC 113

Shortages have persisted since 2022

While the pro-fibrogenic effects of smoking are well-documented, it is worth noting that the impact of tobacco on the degree of steatohepatitis is less marked, with no significant differences in MASH resolution [64]

The logic is sound: you get concentrated local delivery to the target tissue plus systemic support for the repair machinery behind it

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By mimicking the natural hormone GLP-1, Wegovy acts on the brain and digestive system to suppress appetite, delay gastric emptying, and promote early satiety after meals