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If suitable nanoparticle homogeneity is not obtained on direct synthesis, then size-exclusion chromatography is used to produce highly uniform drug-containing particles that are freed of other components involved in their fabrication

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doi: 10.1006/bbrc.2000.4065

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Stria of all ages can then be grown under similar treatment conditions as for SGNs and cochleae as described above for the evaluation of otoprotectant agents