For these compounds to beat the alternatives, the environment must be right
Their increase induces endothelial lesions and the oxidation of LDL and redox-sensitive genes, reaching the monocyte-1 chemo attracting protein and the vascular cell adhesion molecules, molecular mechanisms that are involved in the development of the atherosclerosis
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Leading obesity medicine societies now classify obesity as a chronic disease, and GLP-1 treatment as potentially long-term management, similar to statins for cholesterol or antihypertensives for blood pressure
Susan Spratt, an endocrinologist and the senior medical director of the Population Health Management Office at Duke Health in North Carolina, who was not involved in the studies, applauded the research, saying the findings show that obesity is not a vanity issue. This is about treating a major health problem that reduces significant morbidity and mortality, she said
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