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Structure of a Drosophila Sigma class glutathione S-transferase reveals a novel active site topography suited for lipid peroxidation products

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Novo Nordisk addressed this and developed semaglutide by first changing the fatty chain acid linker to an "OEG" linker, which was observed to result in high receptor potency and high affinity for albumin [26]

A prospective study of acute drug-induced liver injury in patients suffering from non-alcoholic fatty liver disease