In addition to the inter-organ crosstalk orchestrated by G49 that ultimately leads to UCP-1-dependent BAT activation, our results provide evidence of cell-autonomous effects in differentiated BA that were manifested by increases in lipolysis, brown-related gene expression profile, UCP1 protein levels, increased respiratory capacity and FAO
Regimens with similar effectiveness included (i) BPC 157 dissolved in saline (10 g, 10 ng/kg body weight), (ii) pentadecapeptide BPC 157 in neutral cream (1.0 or 0.01 g dissolved in distilled water/g commercial neutral cream)
Common side effects include upper respiratory tract infections, sore throat, and headaches
Congress should: Suspend the policy immediately pending review, investigate how DHA justified such a clear violation of statutory and regulatory text, clarify by statute that no drug on the uniform formulary may be denied to Tricare for Life beneficiaries if it is available to any other Tricare enrollee and require public accountability by compelling DOD to explain why it used a regulation that expressly excludes Tricare for Life to strip benefits from older veterans
Dotted line indicates time of randomization
Philadelphia, PA: Lippincott Williams & Wilkins (2011)