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This antioxidative effect is also observed with caffeine and paraxanthine [10], which are known to upregulate endogenous antioxidant systems [43], thereby protecting neurons from oxidative damage [44]

Less common: Dizziness, hyperactivity, difficulty swallowing

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A potent endogenous antioxidant, glutathione is essential for phase I and phase II liver detoxification.* Unfortunately, lifestyle issues and conditions that negatively affect liver health usually result in a decreased amount of liver glutathione

However, some nerve damage from long-term deficiency may be permanent

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