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Figure 1 1.2 Adipogenesis Adipogenesis is the molecular and cellular process by which undifferentiated cells, typically mesenchymal stem cells, differentiate and develop into mature adipocytes (fat cells) capable of storing and releasing lipids ( Adipocytes originate from mesenchymal stem cells (MSCs), which are multipotent cells that can differentiate into various cell types, including adipocytes, osteoblasts, and chondrocytes through a complex and multi-step process comprising a network of transcription factors ( Adipocyte differentiation can be induced in cell culture by the stimulation of MSCs with isobutylmethylxanthine (IBMX), dexamethasone, and insulin, in particular for the murine 3T3-L1 cell line ( Adipogenesis can be assessed and quantified in vitro by measuring endpoints such as the degree of intracellular lipid accumulation, the expression of adipogenic genes and their corresponding protein products
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