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The MMP-2 and MMP-9 activity assays use a 5-FAM (fluorophore) and QXL520 (quencher) labeled FRET peptide substrate to quantify MMP-2 and MMP-9 activity in the sample

Santos and Roberto Stahl for the technical assistance and Estela Lorza-Gil for establishing pravastatin mice protocol

Acute Stones Once a diagnosis of acute kidney stones is made, the top treatment priority is usually oral or intravenous pain management

Images of cleared embryos were captured using a Zeiss LSM980 laser scanning microscope equipped with differential interference contrast (DIC) optics