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Three mechanistic explanations, not mutually exclusive: Signalling cascade persistence: BPC-157 activates VEGFR2 and FAK-paxillin pathways whose downstream effects (angiogenesis, fibroblast migration, collagen remodelling) unfold over days to weeks after initial receptor engagement

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Most people start feeling a subtle thicker sensation after three to four weeks of twicedaily use, but visible density gains usually become clear around the eightweek mark