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This metabolic shift is hypothesized to enhance mitochondrial function, reduce oxidative stress, and modulate neurotransmitter balance (Lim et al., 2022)

These options require less gastric capacity and are often easier to consume when experiencing nausea or reduced appetite

Contrave combines two active ingredients: Naltrexone (8 mg) and Bupropion (90 mg) per tablet

Choose models and readouts that align with each components preclinical literature mechanism