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Nephropathy is defined as elevated albuminuria, reduced eGFR (usually 25, insulin-resistant women for 26 weeks

In a formal review, the agency concluded that BPC-157: Lacks sufficient safety data and has not been shown to be safe or effective in humans FDA Compounding Memorandum, 2023 The FDA also lists BPC-157 as ineligible for 503B compounding , which prohibits it from being added to compounded medications by outsourcing facilities

For example, a 72-week phase II trial involving 320 patients with MASH, reported MASH resolution rates of up to 59% at the highest dose of 0.4 mg daily as compared to 17% in the placebo group

PMID 21593213

[10] Relative contraindications encompass early polycythemia vera, tobacco amblyopia, and concurrent sensitivity to benzyl alcohol used as a preservative