R.KamermansA.EnzmannG.LyckR.et al (2016)
Rayman MP (2019) Multiple nutritional factors and thyroid disease, with particular reference to autoimmune thyroid disease
In: Handbook of Medical and Health Sciences in Developing Countries: Education, Practice, and Research
Solubility: Water (warm water)
Induced degradation of GPX4 In addition, the induction of ferroptosis can be achieved through the regulation of GPX4 levels, a key regulatory protein for ferroptosis, which has a crucial protective role against the process in organisms
They showed that VitC was able to target common metabolic aberrancies by decreasing adenosine triphosphate (ATP) and glucose transporter 1 (GLUT-1) levels, as well as by dissipating the mitochondrial membrane potential, which could sensitize KRAS mutant CRC cells to current treatments such as chemotherapy