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Proinflammatory cytokine expression in the myocardium has been shown to be reduced by GLP-1R agonists, which directly protects the heart against oxidative stress and inflammation

That does not mean you should ignore it, but it does mean the trajectory is often favorable

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PBMs effectiveness is often attributed to its action on mitochondria, particularly cytochrome c oxidase (CCO) in the electron transport chain (ETC), playing a key role in enhancing oxidative phosphorylation [18]