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The Importance of Copper in GHK-Cu The copper ion in GHK-Cu is not just a carrierits a vital component

Compr Physiol 5(1):115 Zabetian CP, Anderson GM, Buxbaum SG, Elston RC, Ichinose H, Nagatsu T, Kim K-S, Kim C-H, Malison RT, Gelernter J (2001) A quantitative-trait analysis of human plasmadopamine -hydroxylase activity: evidence for a major functional polymorphism at the DBH locus

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Researchers utilise this compound in laboratory models to investigate cellular energy homeostasis and NAD+ salvage pathways

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The reduced incretin effect of GIP in diabetic subjects may be due to the down-regulation of GIP receptor expression, which has been found in pancreatic islets of diabetic Zucker rats and reverted following correction of hyperglycemia [35]