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The resolution of Ibuprofen will determine whether Solara is a 16% EBITDA margin company (dragged down by losses) or a 25%+ margin company that can re-rate meaningfully

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4A, Fig

Pattern HED extrapolation ceiling Daily Dose ~650 mg/day Tablet Math (50 mg) 13 tablets/day included only to show the gap with vendor doses Frequency n/a Notes Allometric scaling from 100 mg/kg/day mouse dose to 80 kg human

Both conditions increase the risk of cardiovascular disease and poor circulation, and those with both may have up to 5 times higher risk of lower extremity amputation and a higher probability of mortality at a younger age