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Similarly, in a phase 2 study of survodutide (GLP-1 RA/glucagon RA) in MASH with F1-3, 62% had improvement in MASH and 34% had improvement in fibrosis compared to 14% improvement in MASH and 22% in fibrosis in the placebo group [9]
Functional effects in the pancreas include the glucose-dependent release of insulin, as well as an up-regulation of the biosynthesis of insulin, glucokinase, and glucose transporters
These issues are not related to tirzepatide and may require tests or treatment from an ear, nose, and throat (ENT) doctor
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