It's the salt modification, which is studied for potentially better stability in the digestive environment
Inhibition was characterized by cancer cell apoptosis and induction of oxidative damage to tumor cell DNA (8-OHdG), but not in normal tissues [76]
The choice depends on specific research questions and target tissue types
Thus, this reflects how the tumour environment helps determine tumour metabolism, highlighting the importance of studying metabolic alterations in a physiological context
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Moreover, these mentioned characteristic alterations are inter-related, with bi-directional feedback, for example, high proliferation rate of growing solid tumor mass would exhaust the local supply of O 2 sooner