By the studys end, patients in all three tirzepatide groups lost around 4-12 more pounds than the semaglutide group and exhibited better diabetic biomarkers.3 The second was published in JAMA Internal Medicine in 2024
Lancet 398 , 18111824 (2021)
Others note the potential for retatrutide, if cleared, to make its way onto obesity treatment guidelines, particularly if studies identify comparable or higher effects
Not only is it helpful for adjusting your prescription as needed, but its important to have a licensed professional available to report side effects to or to ask questions about your care plan (rather than relying on an internet search)
GLP-1 is a hormone your body makes that helps control your blood sugar levels and appetite
The decreased production of estrogen in patients receiving GLP-1RA inhibits the collagen synthesis and increases the activity of metalloproteinase-1, leading to matrix collagen and elastin degradation