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The reduced gluconeogenesis in Pcca -/- (A138T) mice promotes fatty acid oxidation in the liver Interestingly, in the fed condition, Pcca -/- (A138T) mice exhibited a significant reduction (22.7%) in fat mass compared to body weight-matched wild type mice a regular chow diet (Fig

This could theoretically lead to more degradation of the drug in the stomach and slightly reduced bioavailability

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Phosphatidylcholine consists of a glycerol backbone, two fatty acid chains, a phosphate group, and a choline molecule, making it both amphipathic (possessing both hydrophilic and hydrophobic regions) and capable of forming stable bilayers essential for cellular processes

Step 7: Inject Remove both needle caps