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Future research can focus on using specific gene knockout/knock-in animal models and combining single-cell sequencing technology to clarify the spatiotemporal expression patterns and functional differences of p53 in different cell types (such as chondrocytes, synoviocytes, and osteoclasts) and different stages of OA

It also has anti-inflammatory properties to reduce and manage inflammation in the body ( 3 )

By comparison, the diversity changed little when pressure was successively increased, and the medium chemistry kept constant

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