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They promote the efflux of cholesterol from peripheral tissues, including those within arterial walls, and transport it back to the liver for excretion

GLP-1 receptor agonists, including liraglutide and exenatide, have been associated in some studies with indirect improvements in fertility-related markers in women with obesity-related conditions such as polycystic ovary syndrome (PCOS) for example, improvements in ovulatory function, androgen levels, and menstrual regularity

On average, semaglutide is associated with greater total weight loss in clinical trials, roughly 15 percent over 68 weeks, compared with the roughly 5 to 10 percent typically seen with short-term phentermine over about 12 weeks