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Impairment of Fertility In chronic toxicity studies in juvenile and adult rats and dogs, administration of valproate resulted in testicular atrophy and reduced spermatogenesis at oral doses of 400 mg/kg/day or greater in rats (approximately equal to or greater than the maximum recommended human dose (MRHD) on a mg/m 2 basis) and 150 mg/kg/day or greater in dogs (approximately equal to or greater than the MRHD on a mg/m 2 basis)

The composition of the gut microbiota throughout life, with an emphasis on early life

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Open communication between patients and clinicians from treatment planning through survivorship is essential

Personalization is at the heart of modern medical care, ensuring your weight management plan fits your life and your goals