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[26] In one study, nine of 11 patients with APL entered complete remission after treatment with 45 mg/m2 daily oral dose of RA

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DOI:10.1001/archderm.94.3.355 [ Links ] 71

Speed of Results: Which Works Fastest Based on clinical research: Kojic acid : 2-4 weeks for initial results, faster visible changes Glutathione : 4-8 weeks for noticeable changes with consistent use Alpha arbutin : 6-12 weeks for significant improvement, but results are more stable Safety Profile and Suitability for Sensitive Skin Alpha arbutin : Safest option, suitable for all skin types Glutathione : Generally safe, rare side effects Kojic acid : Highest irritation potential, requires caution Cost-Effectiveness Analysis Alpha arbutin offers the best value effective, stable, and long-lasting

Community protocols document potency degradation at room temperature