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Importantly, with time the majority of relapse-onset patients will transition to a clinically progressive course [known as secondary progressive MS (SPMS)] characterized by cytodegeneration, while the inflammatory component wanes with age (Compston and Coles, 2008)

When combined, ferroptotic lipid peroxidation and MQC failure seem to be proximal upstream factors that establish the Nrf2-NLRP3 rheostat in PD

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It has been demonstrated that Parkinson's disease-affected patients suffer from 100-200 SNpc neuronal damages per day [119]

It helps to form new tissue, aiding in the healing process and minimizing scarring