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Diabetic Ketoacidosis as an Effect of Sodium-Glucose Cotransporter 2 Inhibitor: Real World Insights

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Additionally, the intestinal epithelial barrier typically permits only small molecules to pass into circulation, blocking large peptides even if they survive initial degradation

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These include methotrexate as first-line therapy, with escalation to combination conventional synthetic DMARDs or biological agents if disease activity remains inadequately controlled