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Providers may prescribe FDA-approved GLP-1s for weight loss for eligible overweight or obese patients that are starting or continuing their weight loss journey using a GLP-1
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Participants with normal hepatic function were eligible for inclusion if they were judged to be of general good health by the investigator, based on a medical examination (including physical examination, medical history, vital signs and ECG) and had liver enzyme levels within prespecified limits (alanine aminotransferase upper limit of normal [ULN] + 10%, aspartate aminotransferase ULN + 20% and total bilirubin ULN + 20%)
Any use outside of its approved labeling is considered off-label and is prescribed only when medically appropriate
Diseases such as Scurvy caused by the deficiency of vitamin C are prevented
However, Melanotan II remains unapproved and lacks a defined long-term human safety profile
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