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Catalytic nanodots-driven pyroptosis suppression in nucleus pulposus for antioxidant intervention of intervertebral disc degeneration

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Furthermore, it promotes the polarization of microglia from the pro-inflammatory M1 phenotype (indicated by a decrease in the CD86 + ratio) to the anti-inflammatory M2 phenotype (indicated by an increase in the CD206 + ratio)

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Genet Dev