Dihexa amplifies HGF/c-Met signaling to promote the physical construction of new synaptic connections (spinogenesis)
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WO2014052766A1 - Hepatocyte growth factor mimics as therapeutic agents - Google Patents Hepatocyte growth factor mimics as therapeutic agents Download PDF Info Publication number WO2014052766A1 WO2014052766A1 PCT/US2013/062199 US2013062199W WO2014052766A1 WO 2014052766 A1 WO2014052766 A1 WO 2014052766A1 US 2013062199 W US2013062199 W US 2013062199W WO 2014052766 A1 WO2014052766 A1 WO 2014052766A1 Authority WO WIPO (PCT) Prior art keywords hgf dihexa group mimics nle Prior art date Legal status (The legal status is an assumption and is not a legal conclusion
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In a 2013 study by Korenevsky et al., the researchers administered a combination of melatonin and epithalon to female rats exposed to suboptimal environmental factors, such as light pollution, finding that the combined therapy rectified various impairments of the hypothalamic-pituitary-gonadal axis [13]