AS, ED, DN, DA, RB, and MN edited the manuscript
Ethics declarations Competing interests The authors declare that they have no competing interests
Three pilot studies with very small sample sizes, a Phase II trial whose results remain unpublished, and a regulatory record that reflects the FDA's own assessment that sufficient human safety data do not exist that is the complete ledger as of 2025
13 Choosing Wisely Campaign The American Board of Internal Medicines global Choosing Wisely (CW) Campaign encourages patient engagement and healthcare provider conversation to choose care that is evidence-based, necessary, and free from harm
Understand the actual risks and benefits
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