Specifically, Mn overexposure has been shown to promote the exosomal transmission of -synuclein between neurons and microglia, triggering neuroinflammatory responses in vitro and in vivo (Harischandra et al., 2019
Methods The current systematic review was conducted in accordance with Preferred Reporting Items for Systematic Reviews and Meta-Analysis (PRISMA) guidelines
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Tsokos GC, Lo MS, Costa Reis P, Sullivan KE (2016) New insights into the immunopathogenesis of systemic lupus erythematosus
Of note, 2 studies shared an identical cohort and adhered to the same drug administration protocol [11, 12]