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When the thyroid is disrupted all sorts of things can go wrong
[1] When used in combination with sulfonylureas or insulin, there is an increased risk of hypoglycaemia, and dose adjustments of these medications may be required
Unlike previous incretin-based therapies, it targets three critical pathways in metabolic regulation
The ATTAIN-MAINTAIN trial demonstrated that patients switching from tirzepatide to orforglipron maintained most of their weight loss, with modest regain of approximately 5 kg on average
The immunology of stress and the impact of inflammation on the brain and behaviour
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