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They performed experiments on human hepatic L02 cells treated with CdCl2 and found that Drp1 and retinoblastoma (RB) protein levels were increased and translocated to mitochondria in CdCl 2 -treated cells

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Prior studies have detected the increased IL-6 when challenged with an intravenous UA solution in healthy volunteers and this variation cannot be reversed by rasburicase which is an effective UA-lowering drug (70)