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Excess fat also disrupts digestion, making it harder to achieve a lean midsection

While treatment with SSRIs may bring their ghrelin levels back to a more normal range, it may not impact their leptin (satiety) levels - though studies addressing these topics have been very small

However, patients taking antihypertensive medications may require dose adjustments as weight loss progresses, and dehydration from gastrointestinal side effects can potentially lead to reduced blood pressure in some cases

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Brautigam P, Foldi E, Schaiper I, Krause T, Vanscheidt W, Moser E