Data obtained in a rat model and in rat H9c2 cardiac cells showed that BBR treatment leads to upregulation of SIRT1 and downregulation of p66shc expression both in vivo and in vitro , resulting in suppression of ROS production, apoptosis, and mitochondrial damage, and improving cardiac dysfunction
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The cells incorporate cysteine and most of the intracellular cysteine is incorporated into the synthesis of GSH
35661 Bypass graft, with vein, femoral artery to aboveknee popliteal artery