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Originally developed to help treat type 2 diabetes, GLP-1 drugs have proven effective at promoting weight loss , at least for as long as the medications remain in use

The IgD isotype was chosen as the scaffold for our universal chimeric BCR to maximize the probability of surface expression and appropriate signal transduction upon antigen binding without depending on the ancillary Ig and Ig molecules 20 required for IgM-mediated BCR signal transduction

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