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Untreated cells are indicated as UTC and ethanol-treated cells as ETC

There is evidence showing that GLP-1RAs can reduce the expression of cell apoptotic markers Bcl-2-associated x (Bax) and caspase-3 while upregulating Bcl-2 [99, 100], as well as protecting against lipotoxic stress via phosphoinositide 3-kinase (PI3K)/Akt/forkhead box proteins O1 (FoxO1) pathway [101]

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GPx, glutathione perioxidase

Ozempic and Wegovy are generally taken as a weekly injection, self-administered at home