For more detailed information, refer to the official announcements from BCBSM and BCN (Link).
The term was coined decades ago to describe taking tiny, microgram-size doses of psychedelic drugs like LSD for cognitive benefits without hallucinating
It is specifically meant to be used as a type 2 diabetes medication to manage blood glucose levels
Someone carrying extra weight who still runs half marathons, with normal blood sugar, normal labs, and good energy, has what the commission calls preclinical obesity: a state worth watching, with elevated future risk, but not necessarily one that demands aggressive treatment today
Work in animals provides evidence for each of these putative pathways, supporting that ghrelin can act locally in the hypothalamus (i.e., paraventricular nucleus, arcuate nucleus), NTS, and potentially, in the hippocampus and VTA (Perello et al., 2019)
The exact BMI thresholds the FDA sets for GLP-1 medications The FDA approval language is remarkably consistent across GLP-1 medications approved for weight management
