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Pharmacokinetics : The half-life was determined to be approximately six days, supporting once-weekly dosing

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Semaglutide and Cardiovascular Outcomes in Obesity without Diabetes. New England Journal of Medicine 389(24):22212232

The Wegovy FDA label advises discontinuing semaglutide at least two months before a planned pregnancy due to the long half-life and absence of adequate human safety data [5]

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