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As the condition worsens, fever and jaundice may develop, signaling a blocked bile duct or infection

PEG modification increased the stability of protein and peptide drugs, increased the solubility, reduced the immunogenicity, prolonged the residence time in blood, reduced the protease degradation, and reduced the frequency of drug use

This will generally completely remove the tumour as well as guide the need for any further investigations or treatment once the histology is known

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These drugs are often the first line of defense, offering a convenient and non-invasive option for patients